INHIBITORS OF RETROVIRAL PROTEASES

摘要

Compounds useful as inhibitors of retroviral proteases characterized by structure (I), wherein the X<1> groups may consist of 0 to 2 alpha -amino acid groups terminally substituted by hydrogen or one of a number of end groups, and the R<1> group can be selected from a wide variety of hydrocarbon radicals. Compounds which exhibit a protease activity inhibition constant Ki of less than 50 are desired.