| 发明名称 |
Immunoglobulin conjugates |
| 摘要 |
A conjugate comprising a vinca moiety convalently linked at the 4-position via a group of the formula -OCOXCO- where X represents a single chemical bond or an optionally substituted C1-10 chain, to an immunoglobulin or an immunoglobulin fragment. The conjugates are useful in the treatment of cancer.
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| 申请公布号 |
US4845200(A) |
申请公布日期 |
1989.07.04 |
| 申请号 |
US19860877598 |
申请日期 |
1986.06.23 |
| 申请人 |
LILLY INDUSTRIES LIMITED |
发明人 |
CULLINAN, GEORGE J.;ROWLAND, GEORGE F.;SIMMONDS, ROBIN G. |
| 分类号 |
G01N33/531;A61K39/395;A61K47/48;C07D519/04;C07K17/02;C12Q1/04 |
主分类号 |
G01N33/531 |
| 代理机构 |
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