| 发明名称 |
Prepn. of oxo-di:hydroxy piperazino:quinoline carboxylic acid cpds. |
| 摘要 |
(A) Quinoline-carboxylic acid cpds. of the formula (I) and their salts are prepd. by reacting cpds. of the formula (V) with piperazine cpds. of the formula (VI) or their salts to give cpds. of the formula (VII) and then hydrolysing these. (B) Borate cpds. of the formula (VIII) are new. - R1 and R2 are each 2-6C aliphatic acyloxy opt. halogen-substd. or 7-11C aromatic acyloxy; R is H or CH3. - Cpds. of formula (V) are also claimed.
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| 申请公布号 |
ES2002445(A6) |
申请公布日期 |
1988.08.01 |
| 申请号 |
ES19860003514 |
申请日期 |
1986.12.19 |
| 申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. |
发明人 |
HERMECZ ISTVAN;KERESZTURI GEZA;VASVAR NEE DEBRECZI LELLE;HORVATH AGNES;BALOGH MARIA;KOVACS GABOR;MESZAROS ZOLTAN;KITLI PETER;SIPOS JUDIT |
| 分类号 |
A61K31/47;A61K31/69;C07D215/56;C07F5/04;(IPC1-7):C07D215/56 |
主分类号 |
A61K31/47 |
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