发明名称 A PROCESS FOR PREPARING ARYCYCLOBUTYLALKYLAMINES
摘要 <p>Compounds of formula I <IMAGE> and pharmaceutically acceptable salts thereof; in which R1 and R2, which are the same or different, are H or an optionally substituted hydrocarbon group or R1 and R2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring; R3 is an optionally substituted aromatic hydrocarbon group; and R4 is a hydrocarbon group containing at least one substituent selected from the group consisting of hydroxy and acylated derivatives thereof, optionally substituted alkoxy groups, optionally substituted cycloalkyloxy groups, optionally substituted alkylenedioxy groups, oxo and groups of formula S(O)pR5 in which p is 0, 1 or 2 and R5 is an alkyl group, said hydrocarbon group being optionally substituted by additional substituents, are useful in the treatment of depression.</p>
申请公布号 IN162780(B) 申请公布日期 1988.07.09
申请号 IN1013MA1985 申请日期 1985.12.17
申请人 BOOTS CO., PLC 发明人 HOUSLEY JOHN ROSINDALE;JEFFERY JAMES EDWARD;JOHNSTON DAVID NORMAN;SARGENT BRUCE JEREMY
分类号 C07D307/52;A61K31/135;A61K31/16;A61K31/165;A61K31/215;A61K31/22;A61K31/33;A61K31/4409;A61K31/4418;A61K31/445;A61K31/535;A61K31/5375;A61P25/24;A61P25/26;C07C45/63;C07C49/567;C07C67/00;C07C213/00;C07C215/38;C07C217/48;C07C217/74;C07C219/22;C07C225/18;C07C231/00;C07C231/12;C07C235/06;C07C313/00;C07C317/28;C07C323/29;C07D211/14;C07D211/30;C07D211/70;C07D213/30;C07D295/073;C07D295/08;C07D295/084;C07D295/10;C07D295/13;C07D295/145;C07D295/185;C07D317/28;C07D319/06;(IPC1-7):C07C87/28 主分类号 C07D307/52
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