| 摘要 |
PURPOSE:The titled remedy that is made by making a TNF-inducer act on the cells resulting from transplantation of human-originating cells, which can produce TNF and is established as a cultured strain, in a body of animals other than human, thus containing TNF. CONSTITUTION:Human-relating cells, which can produce TNF and are established as a cultured strain, such as Namalva cells are transplanted in the body of a warm- blood animal such as bird such as chicken or a mammarian such as dog or cat or inoculated in a diffusion chamber to proliferate, as receiving the supply of body fluid containing nutrients from the animal. Then, a TNF inducer is made to act on the resultant cells in virto or in vivo. Thus, the formation of TNF is induced in high activity and the TNF is separated and purified in a large amount. The TNF is used to given a remedy for malignant tumotors. The preparation is used in a form of capsules, tablets as an enteric coating, a suppository, injection solution, further collunarium, eye drops or ointment. |
