FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA 5-R,S-TRANS-AMINO-3,4,5,6-TETRAHYDRO-1H -CYKLOHEPT/C,D/INDOL-6-OLDERIVAT OCH AV DERAS SYRAADDITIONSSALTER.

摘要

Novel trans cyclohept[c,d]indolols of the formula I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and R1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having hypotensive and antihypertensive activity and a process for their preparation.