| 摘要 |
PURPOSE:To provide the titled inhibitor containing a pyrazine derivative and effective also for the prevention of cancer metastasis. CONSTITUTION:The objective platelet coagulation inhibitor can be produced by using the compound of formula as an active component. It is useful as a preventive for diseases caused by the coagulation of platelet, i.e. thrombosis, metastasis of cancer, etc. Dose: 30-600mg daily, if necessary in 1-3 divided doses. It is administered preferably by oral administration, however, it can be administered also by intravenous injection. It is used in the form of tablet, powder, capsule, granule, etc., using a carrier or diluent such as calcium carbonate, calcium phosphate, starch, sucrose, lactose, talc, magnesium stearate, etc. It may be used as a liquid medicine such as suspension in oil, syrup, etc., or may be stabilized by including the compound with cyclodextrin.
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