| 摘要 |
PURPOSE:A membrane composition, containing a phospholipid and/or hydrogenated phospholipid, and having improved biodegradability and compatibility with living bodies. CONSTITUTION:A membrane composition obtained by dissolving a phospholipid derived from egg yolk or plant or/and a hydrogenated phospholipid in a solvent, e.g. hexane, lower aliphatic halogenated hydrocarbon such as chloroform or lower aliphatic alcohol such as ethanol, dispersing or dissolving an active substance, e.g. fat-soluble vitamin, water-soluble vitamin or nonsteroidal hormone, and drying the resultant dispersion or solution to give a film. The addition of a high polymer e.g. polybutene or chlorinated paraffin, or oily substance, e,g. liquid paraffin or squalane, permits the adjustment of strength, elasticity of the film and releasability of the active substance, etc. EFFECT:Improved affinity for the skin and excellent absorbability and solubility of the active constituent. The composition is very stable with time, and can be incorporated in a large amount even in the liquid form. |
