摘要 |
Fluorine contg. 1,4-dihydropyridine I (R=H, substituted alky, aralkyl; R1,R6=substituted alkyme; R4=alkyl, nitro, cyano, trifluoromethyl, halo, azido, trifluoromethoxy, alkyl, alkoxy, alkylmercapto, SO2-alkyl, substituted aryl, or quinolyl, pyridyl, thienyl, furyl substituted by alkyl, halo; R5=alkyl substituted by halo, aminoalkyl substituted possibly by aralkyl, alkenyl, alkynyl, alkoxyalkyl, -CHR2R3; R2, R3=side, straight chain, cyclic aliphatic hydrocarbon substituted by Fl-3 contg. carbon; R2,R3=C4-C7 saturated isocyclic ring was formed with CH) was prepd. for use as coronary vasodilator and as antihypertensives.
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