| 摘要 |
The cephalosproins I(R1 = H, CH3O; R2 = phthalimido, succineimido; R13 = -CO-C6H5, C1-4 alkyl, etc.), useful as fungicides, were prepd. by reacting compd. II (R = C1-3 alkyl, C4-6 cycloalkyl, amino) with S-contg. uncleophilic reagent III (R14 = H, or thiourea with R13) in anhydrous arg.solvent. Thus, 3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-7-(2-(2-thienyl)acetamido)-3-cephem-4-carboxylic acid was prepd. from 7-(2(2-thienyl)acetamido)cephalosporanic acid and l-methyl-1H-tetrazol-5-thiol in acetonitrile.
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