发明名称 |
VERFAHREN ZUR HERSTELLUNG VON MIKROKUGELN |
摘要 |
Microspheres of core material and polymer are produced by adding a phase separation agent to a medium comprising a solution of the polymer and a solution or dispersion of the core material at a temperature of -40 to -100 DEG C. Preferably the core material is a drug and the polymer is biodegradable. The low temperature phase separation step prevents uncontrolled agglomeration of the microspheres. |
申请公布号 |
ATA612478(A) |
申请公布日期 |
1983.01.15 |
申请号 |
AT19780006124 |
申请日期 |
1978.08.23 |
申请人 |
SANDOZ-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. |
发明人 |
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分类号 |
A61K9/58;A01N25/28;A61K8/04;A61K8/85;A61K9/16;A61K9/50;A61K9/52;A61K31/48;A61P43/00;A61Q13/00;A61Q15/00;B01J13/02;B01J13/08;(IPC1-7):B01J13/02 |
主分类号 |
A61K9/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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