| 摘要 |
Compounds of formula I …<CHEM>… wherein… R is alkyl, alkenyl, cycloalkyl, cycloalkylalkyl or optionally substituted aryl, aralkyl or aralkenyl,… R1 is hydrogen or a substituent,… R2 is hydrogen or has the significance indicated above for R,… A is alkylene,… X is a bond or imino,… Y is an oxygen or a sulfur atom and either Z is an oxygen atom and n is 2 or 3 or Z is a bond and n is 1, 2 or 3, with the proviso that when R2 is cycloalkylalkyl, R is alkyl and X is a bond… then R1 is other than hydrogen,… or aphysiologically acceptable hydrolyzable derivative thereof having the hydroxy group in the 2 position of the 3-aminopropoxy side chain in esterified form,… in free form or in salt form. …<??>These compounds are useful as cardioselective betaadrenoreceptor blocking agents. |
