HYBRIDCELLINJE FOER FRAMSTAELLNING AV MONOKLONAL ANTIKROPP MOT MAENSKLIGA T-CELLERS ANTIGENER DEN SAOLUNDA FRAMSTAELLDA ANTIKROPPEN SAMT TERAPEUTISKA OCH DIAGNOSTISKA METODER I VILKA ANTIKROPPEN ANVAENDS

摘要

Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.