| 摘要 |
A process for the preparation of sulfur-containing N-benzyl-amino acids of the formula <IMAGE> wherein X and Y, which may be identical to or different from each other, are each hydrogen or halogen; R1 is hydrogen or alkyl of 1 to 4 carbon atoms; R2 is hydrogen, alkyl of 1 to 3 carbon atoms, carboxy-lower alkyl or acyl; R3 is hydrogen or acyl; and n is 1 or 2; which comprises the steps of converting anthranilic acid or a halogenated anthranilic acid into the corresponding aldehyde, reacting the aldehyde with a compound of the formula <IMAGE> wherein R1, R2 and n have the meanings previously defined, to form the corresponding Schiff's base, reducing the said Schiff's base, and recovering the reaction product. |
