IMPROVED PROCESS FOR THE PREPARATION OF 6-ALPHA-HYDROXY-N-ALKYLAT ED OPIATES.
摘要
<p>The present invention is directed to the conversion of a 6-keto morphinan to a6-alpha-hydroxy morphinan in the presence of a ruthenium, rhodium, or iridiumasymmetric catalyst and a hydrogen source.</p>
申请公布号
MX2008013842(A)
申请公布日期
2009.03.06
申请号
MX20080013842
申请日期
2008.05.02
申请人
MALLINCKRODT INC.
发明人
GARY L. CANTRELL;FRANK W. MOSER;PETER X. WANG;CATHERINE E. THOMASSON;CHRISTOPHER W. GROTE;TAO JIANG
