| 发明名称 |
ACTIVITY-DEPENDENT NEUROTROPHIC FACTOR |
| 摘要 |
<p>The present invention relates to a purified non-neuronal activity-dependent neurotrophic factor (ADNF) protein that increase the survival of spinal cord neuron cells, cerebral cortical cells and hippocampal neuron cells which has a molecular weight of 16,000 to 18,000 Daltons as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis, and a basic pI of about 8.1.</p> |
| 申请公布号 |
EP0662092(B1) |
申请公布日期 |
2005.03.23 |
| 申请号 |
EP19920913651 |
申请日期 |
1992.04.22 |
| 申请人 |
THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
BRENNEMAN, DOUGLAS, E.;GOZES, ILLANA |
| 分类号 |
A61K38/00;A61K39/395;A61P25/00;A61P31/12;A61P31/18;C07K1/00;C07K14/435;C07K14/475;C07K14/52;C07K16/00;C07K16/22;C07K16/24;C12P21/08;(IPC1-7):C07K14/00 |
主分类号 |
A61K38/00 |
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