| 发明名称 |
Optically active carbonates as precursors of (+)-zopiclone |
| 摘要 |
In the present invention new compounds of formula II, in enantiomerically enriched forms, are described for the first time, where R<SUP>1 </SUP>is chloroalkyl. The present invention also includes several new enzymatic processes for the resolution of the enantiomers of the aforementioned carbonates of formula II from the corresponding racemic mixture. The transformation of these carbonates into zopiclone enantiomerically enriched, constitutes an additional aspect of the invention.
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| 申请公布号 |
US6969767(B1) |
申请公布日期 |
2005.11.29 |
| 申请号 |
US20030405998 |
申请日期 |
2003.04.02 |
| 申请人 |
ASTUR PHARMA, S.A. |
发明人 |
BAYOD JASANADA MIGUEL;SANCHEZ PEDREGAL VICTOR M.;GOTOR SANTAMARIA VICENTE;BRIEVA COLLADO M. ROSARIO;FERNANDEZ SOLARES LAURA;DIAZ SIERRA MONICA;GUISAN SEIJAS JOSE MANUEL;PALOMO CARMONA JOSE MIGUEL;FERNANDEZ-LAFUENTE ROBERTO |
| 分类号 |
C07B57/00;C07D213/72;C07D239/02;C07D487/04;C12P41/00;(IPC1-7):C07D239/02 |
主分类号 |
C07B57/00 |
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