发明名称 |
4'-C-ETHYNYL PYRIMIDINE NUCLEOSIDE COMPOUNDS |
摘要 |
The invention provides 4'-C-ethynyl pyrimidine nucleosides (other than 4'-C-ethynylthymidine) represented by formula ¢I!: (see above formula) wherein B represents a base selected from the group consisting of pyrimidine and derivatives thereof; X represents a hydrogen atom or a hydroxyl group; and R represents a hydrogen atom or a phosphate residue; and a pharmaceutical composition containing any one of the compounds and a pharmaceutically acceptable carrier. Preferably, the composition is used as an anti-HIV agent or a drug for treating AIDS.
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申请公布号 |
CA2308192(A1) |
申请公布日期 |
2000.11.12 |
申请号 |
CA20002308192 |
申请日期 |
2000.05.12 |
申请人 |
YAMASA CORPORATION |
发明人 |
MITSUYA, HIROAKI;SHIGETA, SHIRO;OHRUI, HIROSHI;KOHGO, SATORU;KODAMA, EIICHI;MACHIDA, HARUHIKO |
分类号 |
A61P31/18;C07H19/06;C07H19/16;(IPC1-7):C07H19/06;C07H19/052;C07H19/23;A61K31/437;A61K31/706 |
主分类号 |
A61P31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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