USES OF THE BORRELIACIDAL EPITOPE(S) OF BORRELIA BURGDORFERI OUTER SURFACE PROTEIN C (OSPC) AS VACCINE
摘要
An OspC Dra fragment fusion peptide isolated from Borrelia burgdorferi is described herein for the prevention, treatment and early diagnosis of Lyme disease in humans and other animals. This invention also relates to a screening method detecting anti-Osp borreliacidal antibody activity, and antibodies reacting with a protein fragment encoded by a DraI-SmaI DNA fragment of OspC.
申请公布号
WO0006745(A1)
申请公布日期
2000.02.10
申请号
WO1999US17270
申请日期
1999.07.30
申请人
GUNDERSEN LUTHERAN MEDICAL FOUNDATION, INC.;CALLISTER, STEVEN, N.;LOVRICH, STEVEN, D.;SCHELL, RONALD, F.;JOBE, DEAN, A.
发明人
CALLISTER, STEVEN, N.;LOVRICH, STEVEN, D.;SCHELL, RONALD, F.;JOBE, DEAN, A.