发明名称 IMMUNOMODULATORY PROPERTIES OF MULTIPOTENT ADULT PROGENITOR CELLS AND USES THEREOF
摘要 PROBLEM TO BE SOLVED: To provide therapeutic agents for immune function disorders comprising isolated and expanded multipotent cells, neither embryonic nor germ cells.SOLUTION: The therapeutic agent comprises an effective amount of a cell, where the cell is of a normal karyotype, is expressing a telomerase, has undergone at least 10-40 cell doublings in culture, is allogeneic or xenogeneic to the subject, and does not elicit harmful immune response in the subject, and the agent is administered adjunctively to one or more of other therapies, for example, the cell is adjunctively used in transplant therapy for immunosuppression.SELECTED DRAWING: None
申请公布号 JP2016135763(A) 申请公布日期 2016.07.28
申请号 JP20150246808 申请日期 2015.12.18
申请人 ATHERSYS INC;OREGON HEALTH & SCIENCE UNIV 发明人 ROBERT DEANS;VAN'T HOF WOUTER;RICHARD MAZIARZ;MAGDALENA KOVACSOVICS;PHILIP STREETER
分类号 A61K35/12;A61K35/14;A61K35/26;A61K35/28;A61K35/30;A61K35/407;A61K35/50;A61K35/51;A61P7/00;A61P7/06;A61P19/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06 主分类号 A61K35/12
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