METHOD FOR SCREENING CANCER PREVENTION AGENT OR ANTICANCER AGENT USING MORPHOLOGICAL CHARACTERISTICS OF LUTERIAL

摘要

The present invention relates to a method for screening an anticancer agent or a cancer preventive agent, comprising the steps of: (a) isolating mutant luterial or normal luterial from a body fluid extracted from a patient or a normal person; (b) treating the isolated mutant luterial with anticancer agent candidates or cancer preventive agent candidates; and (c) either selecting, as the anticancer agent, a candidate that reduces the size or changes the shape or increases the mobility of the mutant luterial, compared to the control mutant luterial upon treatment with the candidate, or selecting, as the cancer preventive agent, a candidate that suppresses the increase in size, minimizes the change in shape or maintains the mobility of luterial, compared to the control luterial, upon treatment with the candidate.

主权项

1. A method for screening an anticancer agent, comprising the steps of:
(a) isolating mutant luterial from a body fluid extracted from a patient; (b) treating the isolated mutant luterial with anticancer agent candidates; and (c) selecting, a candidate as the anticancer agent by testing its ability to reduce the size, change the shape or increase the mobility of the mutant luterial compared to a control mutant luterial without treatment.