发明名称 COMPOSITIONS AND METHODS FOR THERAPY OF CYSTIC FIBROSIS
摘要 A promoter for high level and sustained expression is provided which can be used for gene expression of chosen sequences in general. In particular, a nucleic acid construct comprising a hCEF1 promoter operably linked to a sequence for expression is provided, where the hCEF1 promoter comprises: (i) a human CMV enhancer operably linked to a human EF1 a promoter; (ii) a functional fragment of (i); or (ii) a functional variant of (i) or (ii).
申请公布号 PT2007895(E) 申请公布日期 2014.12.12
申请号 PT20070732165T 申请日期 2007.03.28
申请人 IMPERIAL INNOVATIONS LTD 发明人 STEPHEN HYDE;DEBORAH GILL
分类号 C12N15/85;A61K48/00 主分类号 C12N15/85
代理机构 代理人
主权项
地址