发明名称 DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE
摘要 Provided is an agent for treating or preventing a corneal endothelial disorder wherein cell proliferation is required. More specifically, provided is an agent for treating or preventing a corneal endothelial disorder, wherein cell proliferation is required, said agent comprising a p38MAP kinase inhibitor. In a preferred embodiment, the corneal endothelial disorder is a wound. In a preferred embodiment, the p38MAP kinase inhibitor is soluble in water. The p38MAP kinase inhibitor may comprise 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazole-5-yl]pyridine (SB203580) or a salt thereof.
申请公布号 US2016331736(A1) 申请公布日期 2016.11.17
申请号 US201415034710 申请日期 2014.11.13
申请人 THE DOSHISHA 发明人 KOIZUMI Noriko;OKUMURA Naoki;KINOSHITA Shigeru
分类号 A61K31/4439;A61K31/437;A61K31/4418;A61K31/44;A61K31/167;A61K31/5377 主分类号 A61K31/4439
代理机构 代理人
主权项 1. A therapeutic or prophylactic drug for a corneal endothelial disease, disorder or condition requiring cell proliferation, suppression of a cellular disorder or suppression of cellular senescence, comprising a p38 MAP kinase inhibitor.
地址 Kyoto-shi, Kyoto JP