发明名称 |
DRUG FOR TREATING CORNEAL ENDOTHELIUM BY PROMOTING CELL PROLIFERATION OR INHIBITING CELL DAMAGE |
摘要 |
Provided is an agent for treating or preventing a corneal endothelial disorder wherein cell proliferation is required. More specifically, provided is an agent for treating or preventing a corneal endothelial disorder, wherein cell proliferation is required, said agent comprising a p38MAP kinase inhibitor. In a preferred embodiment, the corneal endothelial disorder is a wound. In a preferred embodiment, the p38MAP kinase inhibitor is soluble in water. The p38MAP kinase inhibitor may comprise 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazole-5-yl]pyridine (SB203580) or a salt thereof. |
申请公布号 |
US2016331736(A1) |
申请公布日期 |
2016.11.17 |
申请号 |
US201415034710 |
申请日期 |
2014.11.13 |
申请人 |
THE DOSHISHA |
发明人 |
KOIZUMI Noriko;OKUMURA Naoki;KINOSHITA Shigeru |
分类号 |
A61K31/4439;A61K31/437;A61K31/4418;A61K31/44;A61K31/167;A61K31/5377 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
1. A therapeutic or prophylactic drug for a corneal endothelial disease, disorder or condition requiring cell proliferation, suppression of a cellular disorder or suppression of cellular senescence, comprising a p38 MAP kinase inhibitor. |
地址 |
Kyoto-shi, Kyoto JP |