发明名称 |
SPATIALLY ADDRESSABLE MOLECULAR BARCODING |
摘要 |
The disclosure provides for methods, compositions, systems, devices, and kits for determining the number of distinct targets in distinct spatial locations within a sample. In some examples, the methods include: stochastically barcoding the plurality of targets in the sample using a plurality of stochastic barcodes, wherein each of the plurality of stochastic barcodes comprises a spatial label and a molecular label; estimating the number of each of the plurality of targets using the molecular label; and identifying the spatial location of each of the plurality of targets using the spatial label. The method can be multiplexed. |
申请公布号 |
US2016253584(A1) |
申请公布日期 |
2016.09.01 |
申请号 |
US201615055445 |
申请日期 |
2016.02.26 |
申请人 |
Cellular Research, Inc. |
发明人 |
Fodor Stephen P.A.;Fan Christina;Fu Glenn;Facer Geoffrey |
分类号 |
G06K19/06 |
主分类号 |
G06K19/06 |
代理机构 |
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代理人 |
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主权项 |
1. A method for determining the number and spatial locations of a plurality of targets in a sample, comprising:
stochastically barcoding the plurality of targets in the sample using a plurality of stochastic barcodes, wherein each of the plurality of stochastic barcodes comprises a spatial label and a molecular label; estimating the number of each of the plurality of targets using the molecular label; and identifying the spatial location of each of the plurality of targets using the spatial label. |
地址 |
Menlo Park CA US |