发明名称 Pyrimidine derivatives
摘要 The invention concerns pyrimidine derivatives of Formula (I) wherein m is 0-3 and each R<1 >is a group such as hydroxy, halogeno, trifluoromethyl and cyano; R<3 >is hydrogen, halogeno or (1-6C)alkyl; n is 0-2 and each R<2 >is a group such as hydroxy, halogeno, trifluoromethyl and cyano; p is 0-4; and Q<1 >is aryl or heteroaryl; or pharmaceutically acceptable salts or in vivo cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
申请公布号 US6846827(B1) 申请公布日期 2005.01.25
申请号 US20020070360 申请日期 2002.03.05
申请人 ASTRAZENECA AB 发明人 CUMMING JOHN GRAHAM
分类号 A61K31/505;A61K31/506;A61K31/5377;A61K31/541;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P3/14;A61P7/00;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P19/04;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P35/04;A61P37/08;A61P39/02;A61P43/00;C07D239/42;C07D239/46;C07D239/47;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D413/14;C07D417/12;C07D417/14;(IPC1-7):C07D239/42 主分类号 A61K31/505
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