| 发明名称 |
Rarbeta selective retinoid compounds for inhibiting gene exp ression promoted by ap1 protein and their use in therapy |
| 摘要 |
Retinoid compounds which repress expression of the gene promoted by AP1 protein but which do not significantly activate expression of the genes having RA-responsive elements in their promoter region through RAR alpha and RAR GAMMA receptor subtypes, are used, with reduced side effects, for treating diseases and conditions which are responsive to therapy with retinoids. |
| 申请公布号 |
AU5484696(A) |
申请公布日期 |
1996.11.18 |
| 申请号 |
AU19960054846 |
申请日期 |
1996.04.15 |
| 申请人 |
ALLERGAN |
发明人 |
SUNIL NAGPAL;TAE K SONG;VIDYASAGAR VULIGONDA;JYOTI ATHANIKAR;ROSHANTHA A CHANDRARATNA |
| 分类号 |
C07D309/12;A61K31/35;A61K31/351;A61K31/443;A61K31/455;A61P9/10;A61P17/00;A61P35/02;A61P43/00;C07D405/12 |
主分类号 |
C07D309/12 |
| 代理机构 |
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