发明名称 Antisense modulation of Notch1 expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of Notch1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Notch1. Methods of using these compounds for modulation of Notch1 expression and for treatment of diseases associated with expression of Notch1 are provided.
申请公布号 US2003224513(A1) 申请公布日期 2003.12.04
申请号 US20020160497 申请日期 2002.05.30
申请人 ISIS PHARMACEUTICALS INC. 发明人 FREIER SUSAN M.;DOBIE KENNETH W.;KOLLER ERICH
分类号 A61K38/00;C12N15/113;(IPC1-7):A61K48/00;C07H21/04;C12N5/00 主分类号 A61K38/00
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