摘要 |
Determination of an analyte in solution when partial fill is detected. A sample is introduced to an electrochemical test strip and a constant potential difference, V app , applied between the electrodes; the applied potential is switched off at time t switch after the first application of potential and before any second application of potential. An analyte-dependent current measurement is made between the electrodes during first or second applications of potential, by:
(a) measuring a first value representative of the current between the electrodes just prior to time t switch or an extrapolated value of this current to a measurement time, t meas ;
(b) measuring voltage change after the applied potential is switched off, and determining the double layer capacitance of test strip; and
(c) comparing the determined double layer capacitance to a reference value. A double layer capacitance less than the reference value indicates that the test strip is only partially filled. |