| 发明名称 |
TRIFUNCTIONAL ANTIGEN-BINDING MOLECULE |
| 摘要 |
The invention relates to a trispecific antigen-binding molecule, wherein the antigen-binding molecule is at least tetravalent and comprises an antigen-binding site having specificity against a first antigen epitope, an antigen-binding site having specificity against a second antigen epitope and two antigen-binding sites having specificity against a third antigen epitope and its use a medicament for tumor therapy. |
| 申请公布号 |
US2017037128(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201615290255 |
申请日期 |
2016.10.11 |
| 申请人 |
Affimed GmbH |
发明人 |
LITTLE Melvyn;ZHUKOVSKY Eugene;ESER Markus;WEICHEL Michael;GANTKE Thorsten;REUSCH Uwe;ELLWANGER Kristina;LE GALL Fabrice |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A trispecific antigen-binding molecule, wherein the antigen-binding molecule is at least tetravalent and comprises an antigen-binding site having specificity against a first antigen epitope, an antigen-binding site having specificity against a second antigen epitope and two antigen-binding sites having specificity against a third antigen epitope. |
| 地址 |
Heidelberg DE |
