发明名称 ANTIBODY CONSTRUCTS FOR CD70 AND CD3
摘要 The present disclosure relates to a bispecific antibody construct comprising a first binding domain which binds to human CD70 on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the disclosure provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the disclosure provides a process for the production of the antibody construct of the disclosure, a medical use of said antibody construct and a kit comprising said antibody construct.
申请公布号 WO2017021354(A1) 申请公布日期 2017.02.09
申请号 WO2016EP68294 申请日期 2016.08.01
申请人 AMGEN RESEARCH (MUNICH) GMBH;AMGEN INC. 发明人 RAUM, Tobias;DEISTING, Wibke;BLUEMEL, Claudia;PANZER, Marc;HOFFMANN, Patrick;NAHRWOLD, Elisabeth;NOLAN-STEVAUX, Olivier;LUTTERBUESE, Ralf
分类号 C07K16/28;C07K16/46 主分类号 C07K16/28
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