軟骨組織再生用温度応答性軟骨細胞含有液性製剤、製造方法及びその利用方法

摘要

PROBLEM TO BE SOLVED: To provide a cartilaginous tissue regeneration medial formulation capable of increasing phenotypic expressions of chondrocytes thereby suppressing inflammation of a recipient site.SOLUTION: In a temperature-responsive chondrocyte-containing fluid formulation, hyaluronic acid grafted to a polymer whose hydration force changes in the temperature range of 0-80°C is dissolved in saline, and 1×10pieces to 1×10pieces of cells are dispersed per ml of the formulation.