MODEL ANIMAL, PREVENTION OF LIFESTYLE-RELATED DISEASE, IMPROVEMENT OR THERAPEUTIC AGENT, INGESTION INHIBITOR, SCREENING METHOD, DETECTION MEDICINE FOR LIFESTYLE-RELATED DISEASE, AND DETECTION METHOD OF LIFESTYLE-RELATED DISEASE

摘要

PROBLEM TO BE SOLVED: To provide a model animal for resistance, suppression or improvement of lifestyle-related diseases, and provide the prevention, improvement or therapeutic agent of the lifestyle-related diseases, etc.SOLUTION: (1) A model animal for resistance, suppression or improvement of lifestyle-related diseases is a non-human mammal in which the expression ability of Mab21l1 gene is suppressed or lost, or the MAB21 L1 protein function encoded by the Mab21l1 gene is suppressed or lost. (2) The model animal for resistance, suppression or improvement of the lifestyle-related diseases is formed by introducing variation in the Mab21l1 gene or an expression regulatory region of the Mab21l1 gene.SELECTED DRAWING: None