MICROFLUIDIC DEVICE FOR REMOVAL OF CONSTITUENTS FROM BLOOD

摘要

The present disclosure concerns a microfluidic device comprising microchannels that have a surface, and a sorbent molecule attached to that surface. In some embodiments, the sorbent molecule is a peptide. In some embodiments, the microchannels comprise an array of offset microchannels. The sorbent molecule may be attached to the surface through a polymer, such as a triblock polymer. As a fluid, such as blood, flows through the device, the sorbent molecule captures constituents from the fluid, and prevents them from being transported downstream. Typically, the sorbent molecule does not destabilize the constituent so that the constituent does not disintegrate causing fragments of constituent return to the fluid stream.