发明名称 Method of treating cancer with a composition containing a C12ORF59 protein
摘要 As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over-expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer.
申请公布号 US9233139(B2) 申请公布日期 2016.01.12
申请号 US201313861879 申请日期 2013.04.12
申请人 Korea Research Institute of Bioscience and Biotechnology 发明人 Kim Semi;Lee Yunhee
分类号 A61K38/17;A61K38/08;A61K38/10;A61K38/16 主分类号 A61K38/17
代理机构 Morgan, Lewis & Bockius LLP 代理人 Morgan, Lewis & Bockius LLP
主权项 1. A method for treating cancer comprising administering to a subject having cancer an effective dose of a protein or a fragment thereof, wherein the protein or fragment thereof comprises at least residue numbers 10 to 17 of SEQ ID NO: 28.
地址 Daejeon KR