发明名称 |
Method of treating cancer with a composition containing a C12ORF59 protein |
摘要 |
As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over-expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer. |
申请公布号 |
US9233139(B2) |
申请公布日期 |
2016.01.12 |
申请号 |
US201313861879 |
申请日期 |
2013.04.12 |
申请人 |
Korea Research Institute of Bioscience and Biotechnology |
发明人 |
Kim Semi;Lee Yunhee |
分类号 |
A61K38/17;A61K38/08;A61K38/10;A61K38/16 |
主分类号 |
A61K38/17 |
代理机构 |
Morgan, Lewis & Bockius LLP |
代理人 |
Morgan, Lewis & Bockius LLP |
主权项 |
1. A method for treating cancer comprising administering to a subject having cancer an effective dose of a protein or a fragment thereof, wherein the protein or fragment thereof comprises at least residue numbers 10 to 17 of SEQ ID NO: 28. |
地址 |
Daejeon KR |