发明名称 |
PGC-1beta-Protein-Function Regulator, Mitochondria-Function Regulator, Anti-Obesity Agent, And Screening Method Therefor |
摘要 |
[Problem];To provide a mitochondria-function regulator effective for treatment or prevention of obesity, and a screening method therefore.;[Solution];The mitochondria-function regulator of the present invention contains, as an active ingredient, a PGC-1β-protein function regulator synoviolin. The screening method of the present invention includes a step for causing a test substance to act on an adipose tissue cell or an individual animal, and measuring or detecting one or more of the following in the adipose tissue cell: (1) expression level of synoviolin; (2) a bond between synoviolin and PGC-1β protein; and (3) the ubiquitination of the PGC-1β protein by synoviolin. |
申请公布号 |
US2015330981(A1) |
申请公布日期 |
2015.11.19 |
申请号 |
US201314655744 |
申请日期 |
2013.12.26 |
申请人 |
NAKAJIMA Toshihiro |
发明人 |
NAKAJIMA Toshihiro;FUJITA Hidetoshi;ARATANI Satoko;YAGISHITA Naoko |
分类号 |
G01N33/573;G01N33/68;C12Q1/68 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
1. (canceled) |
地址 |
US |