发明名称 |
USES OF PARASITE MACROPHAGE MIGRATION INHIBITORY FACTORS |
摘要 |
This invention relates to compositions (e.g. vaccine compositions) which can be used to provide a subject with protective immunity against a parasite infection. The compositions comprise: (i) an immunologically effective amount of a nucleic acid (e.g. a nucleic acid-based vaccine) comprising a sequence which encodes a parasite macrophage migration inhibitory factor (MIF) antigen; (ii) a parasite MIF antigen; or (iii) an antibody which specifically binds to a parasite MIF antigen. The compositions may be used to treat infections and diseases caused by parasitic protozoans, such as a Plasmodium parasite, or parasitic helminths. |
申请公布号 |
WO2015144732(A2) |
申请公布日期 |
2015.10.01 |
申请号 |
WO2015EP56310 |
申请日期 |
2015.03.24 |
申请人 |
YALE UNIVERSITY;GLAXOSMITHKLINE BIOLOGICALS SA |
发明人 |
BUCALA, RICHARD;GEALL, ANDREW |
分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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