Revolving cell culture cartridge and methods of use

摘要

A cell culture device and system can be used for high throughput biological assays to study the biological effect of a test substance. The device and system can include a revolving cartridge having a body including a center aperture and two or more evenly spaced sample wells that are spaced apart from each adjacent sample well by at least the diameter of each sample well. Each sample well can be positioned radially equidistant from the center aperture. Each sample well can have a fluid permeable membrane base configured to fluidly couple a top surface and a bottom surface of the body.

主权项

1. A cell device comprising:
a revolving cartridge having a unitary body defining:
a center aperture; andtwo or more evenly spaced sample wells that are spaced apart from each adjacent sample well by at least the diameter of each sample well, each sample well positioned radially equidistant from the center aperture, wherein each sample well has a top opening formed into the top surface of the unitary body and a bottom opening formed in the bottom surface of the unitary body; anda semi-permeable membrane base in each sample well that is configured to fluidly couple the top surface and the bottom surface of the unitary body.