Method And Device For Combined Detection Of Viral And Bacterial Infections

摘要

A lateral flow assay detects and differentiates between viral and bacterial infections. A combined point of care diagnostic device tests markers for viral infection and markers for bacterial infection, to effectively assist in the rapid differentiation of viral and bacterial infections. In one preferred embodiment, the bacterial marker is CRP. In another preferred embodiment, the viral marker is MxA. In some embodiments, it is unnecessary to lyse the cells in the sample prior to applying it to the device.

主权项

1. A method for determining if an infection is bacterial and/or viral, comprising the steps of:
a) collecting a sample; b) transferring the sample to a sample analysis device comprising:
a reagent zone comprising:at least one first reagent specific to CRP such that, when CRP present in the sample contacts the first reagent, a first labeled complex forms; andat least one second reagent specific to MxA such that, when MxA present in the sample contacts the second reagent, a second labeled complex forms; anda detection zone comprising a first binding partner which binds to the first labeled complex; and a second binding partner which binds to the second labeled complex; and c) analyzing the sample for a presence of CRP and/or MxA; wherein steps b) and c) are performed in approximately ten minutes or less.