| 发明名称 | Biological materials related to CXCR7 | ||
| 摘要 | The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. | ||
| 申请公布号 | US8937164(B2) | 申请公布日期 | 2015.01.20 |
| 申请号 | US201113073044 | 申请日期 | 2011.03.28 |
| 申请人 | Ablynx N.V. | 发明人 | Descamps Francis;Pajuelo Maria Gonzalez;Merchiers Pascal Gerard;Stortelers Catelijne;Vanlandschoot Peter;Van Rompaey Philippe;Smit Martine;Leurs Regorius;Detaille David Andre Baptiste Maussang |
| 分类号 | C07K16/28 | 主分类号 | C07K16/28 |
| 代理机构 | Wolf, Greenfield & Sacks, P.C. | 代理人 | Wolf, Greenfield & Sacks, P.C. |
| 主权项 | 1. A VHH or dAb that comprises an amino acid sequence with the formula 1: FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4 (1);wherein FR1 to FR4 refer to framework regions 1 to 4 and are framework regions of a VHH or dAb; wherein CDR1 is SEQ ID NO: 13; CDR2 is SEQ ID NO: 23; and CDR3 is SEQ ID NO: 33; wherein said VHH or dAb specifically binds to human CXCR7. | ||
| 地址 | Zwijnaarde BE | ||