发明名称 |
METHOD FOR INDUCING ALVEOLAR EPITHELIAL PROGENITOR CELLS |
摘要 |
The purpose of the present invention is to provide a method for stably manufacturing alveolar epithelium progenitor cells from pluripotent stem cells. Specifically, the present invention relates to a method for manufacturing alveolar epithelium progenitor cells, the method comprising: (1) a process for culturing pluripotent stem cells in a culture solution containing activin A and GSK3ß inhibitor; (2) a process for culturing the cells in a culture solution containing BMP inhibitor and TGFß inhibitor; and (3) a process for culturing the cells in a culture solution containing BMP4, retinoic acid and GSK3ß inhibitor. |
申请公布号 |
CA2909230(A1) |
申请公布日期 |
2014.10.16 |
申请号 |
CA20142909230 |
申请日期 |
2014.04.14 |
申请人 |
KYOTO UNIVERSITY |
发明人 |
OSAFUNE, KENJI;GOTOH, SHIMPEI;ITO, ISAO;MISHIMA, MICHIAKI |
分类号 |
C12N5/10;C12N5/071;C12N5/0735 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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