发明名称 METHOD FOR INDUCING ALVEOLAR EPITHELIAL PROGENITOR CELLS
摘要 The purpose of the present invention is to provide a method for stably manufacturing alveolar epithelium progenitor cells from pluripotent stem cells. Specifically, the present invention relates to a method for manufacturing alveolar epithelium progenitor cells, the method comprising: (1) a process for culturing pluripotent stem cells in a culture solution containing activin A and GSK3ß inhibitor; (2) a process for culturing the cells in a culture solution containing BMP inhibitor and TGFß inhibitor; and (3) a process for culturing the cells in a culture solution containing BMP4, retinoic acid and GSK3ß inhibitor.
申请公布号 CA2909230(A1) 申请公布日期 2014.10.16
申请号 CA20142909230 申请日期 2014.04.14
申请人 KYOTO UNIVERSITY 发明人 OSAFUNE, KENJI;GOTOH, SHIMPEI;ITO, ISAO;MISHIMA, MICHIAKI
分类号 C12N5/10;C12N5/071;C12N5/0735 主分类号 C12N5/10
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