发明名称 EPROSARTAN SOLID DISPERSANT IMPROVED BIOAVAILABILITY, ITS FABRICATION METHOD AND THE USE
摘要 The present invention relates to an eprosartan solid dispersant with improved bioavailability, a method for manufacturing the same, and a use thereof and, more specifically, to an eprosartan solid dispersant comprising amorphous eprosartan by including eprosartan, a hydrophilic polymer, and a surfactant via spray drying, a method for manufacturing the same, and a use thereof. The eprosartan solid dispersant is manufactured for eprosartan to have an amorphous crystal structure. The eprosartan solid dispersant can be used as a therapeutic agent for preventing or treating hypertension, congestive heart failure, and renal failure by improving solubility and dissolution rate of eprosartan, thereby improving bioavailability of eprosartan. [Reference numerals] (AA) Eprosartan; (BB) Example 1; (CC) Example 2; (DD) Example 3
申请公布号 KR20140050876(A) 申请公布日期 2014.04.30
申请号 KR20120117246 申请日期 2012.10.22
申请人 THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) 发明人 HUH, KANG MOO;HWANG, JOON SUK
分类号 A61K31/4178;A61K9/10;A61K31/415;A61K47/30 主分类号 A61K31/4178
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