| 发明名称 |
Universal fibronectin type III binding-domain libraries |
| 摘要 |
Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens. |
| 申请公布号 |
US8697608(B2) |
申请公布日期 |
2014.04.15 |
| 申请号 |
US20100850219 |
申请日期 |
2010.08.04 |
| 申请人 |
CAPPUCCILLI GUIDO;CREA ROBERTO;SHEN RANDY;HOKANSON CRAIG A.;KIRK PETER B.;LISTON DAVID R.;PROTELICA, INC. |
发明人 |
CAPPUCCILLI GUIDO;CREA ROBERTO;SHEN RANDY;HOKANSON CRAIG A.;KIRK PETER B.;LISTON DAVID R. |
| 分类号 |
C40B50/06 |
主分类号 |
C40B50/06 |
| 代理机构 |
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