发明名称 |
BISPECIFIC IGG ANTIBODIES AS T CELL ENGAGERS |
摘要 |
The present invention provides human IgG bispecific antibodies, wherein one arm of the antibody binds an epitope on immune effector cells, whilst the other arm targets CLEC12A or a functional equivalent thereof. Pharmaceutical uses of these antibodies against malignancies such as MDS, CML or AML are also provided. |
申请公布号 |
CA2889681(A1) |
申请公布日期 |
2014.04.03 |
申请号 |
CA20132889681 |
申请日期 |
2013.09.27 |
申请人 |
MERUS B.V. |
发明人 |
BAKKER, ALEXANDER BERTHOLD HENDRIK;VAN LOO, PIETER FOKKO;LOGTENBERG, TON |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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