发明名称 |
3,4-dihydro-2H-pyrazino[1,2-A]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
摘要 |
Compounds which are 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
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申请公布号 |
US8513241(B2) |
申请公布日期 |
2013.08.20 |
申请号 |
US201213482626 |
申请日期 |
2012.05.29 |
申请人 |
CERVI GIOVANNI;D'ANELLO MATTEO;PAPEO GIANLUCA MARIANO ENRICO;SALOM BARBARA;NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
CERVI GIOVANNI;D'ANELLO MATTEO;PAPEO GIANLUCA MARIANO ENRICO;SALOM BARBARA |
分类号 |
A61K31/5355;A61K31/501;C07D241/04;C07D413/14 |
主分类号 |
A61K31/5355 |
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