| 发明名称 |
ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST CONNECTIVE TISSUE GROWTH FACTOR AND USES THEREOF |
| 摘要 |
This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.
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| 申请公布号 |
US2013190380(A1) |
申请公布日期 |
2013.07.25 |
| 申请号 |
US201213532254 |
申请日期 |
2012.06.25 |
| 申请人 |
DEAN NICHOLAS M.;FOULKES J. GORDON;O'DONNELL NIALL;BENNETT C. FRANK;FRIER SUSAN M.;ISIS PHARMACEUTICALS, INC.;EXCALIARD PHARMACEUTICALS, INC. |
发明人 |
DEAN NICHOLAS M.;FOULKES J. GORDON;O'DONNELL NIALL;BENNETT C. FRANK;FRIER SUSAN M. |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
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