ULTRAFINE L-CARNITINE, METHODS OF PREPARING THE SAME, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide L-carnitine having a configuration exhibiting high bioavailability by oral administration, and its salt; to provide L-carnitine having a configuration easily preparable by combining another component (for example, an oil-based material) incapable of blending with L-carnitine of bulk, and its salt; and to provide L-carnitine having a configuration exhibiting low hygroscopicity, and its salt.SOLUTION: L-carnitine provided has a particle size such that it substantially passes through a 100 USBS mesh sieve. The L-carnitine exhibits increased bioavailability and low hygroscopicity and may be conveniently formulated with oil-based materials to give a drug product. The L-carnitine and its salt have a novel configuration exhibiting high bioavailability by oral administration.