发明名称 |
Basic protein purification tags from thermophilic bacteria |
摘要 |
The invention is related to a method for purification of recombinant proteins using highly basic proteins from thermophilic bacteria as purification tags for use in a cation-exchange chromatography purification step. The basic proteins may be ribosomal proteins. The recombinant proteins are expressed in eukaryotic or prokaryotic host cells. The purification tag will typically have a pl above about 9 and comprise from about 15 to about 250 amino acid residues. |
申请公布号 |
US8426566(B2) |
申请公布日期 |
2013.04.23 |
申请号 |
US201113309282 |
申请日期 |
2011.12.01 |
申请人 |
SHAW ALLAN CHRISTIAN;BANG SUSANNE;SU JING;NOVO NORDISK HEALTHCARE AG |
发明人 |
SHAW ALLAN CHRISTIAN;BANG SUSANNE;SU JING |
分类号 |
A23J1/00;C07K1/00 |
主分类号 |
A23J1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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