摘要 |
<P>PROBLEM TO BE SOLVED: To provide a nucleic-acid aptamer which has camptothecins binding property. <P>SOLUTION: The camptothecins binder is composed of a nucleic-acid aptamer including: arrangement of the following (i) or (ii); any arrangement with base No. 21 to 50 of either of arrangement No. 28 to 32, 35 to 43 and 45 to 59; arrangement with base No. 21 to 51 of arrangement No. 44; or arrangement with base No. 21 to 48 of arrangement No. 60; wherein (i) is GGGNGGGNGGGNGGG (Arrangement No.1) and (ii) is GGGNGGGNGGGNNGGG (Arrangement No.2). <P>COPYRIGHT: (C)2013,JPO&INPIT |