发明名称 |
NEPRILYSIN INHIBITORS |
摘要 |
In one aspect, the invention relates to compounds having the formula: (I) where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |
申请公布号 |
WO2012166390(A1) |
申请公布日期 |
2012.12.06 |
申请号 |
WO2012US38524 |
申请日期 |
2012.05.18 |
申请人 |
THERAVANCE, INC.;FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE |
发明人 |
FLEURY, MELISSA;GENDRON, ROLAND;HUGHES, ADAM, D.;SCHMIDT, JANE |
分类号 |
C07D213/81;A61K31/4418;A61P9/12;C07D239/28;C07D249/10;C07D261/18;C07D401/06;C07D471/04;C07D487/04;C07D498/04 |
主分类号 |
C07D213/81 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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