发明名称 BISPECIFC ANTIBODIES AGAINST HER2
摘要 Bispecific antibodies which comprise antigen-binding regions binding to two different epitopes of human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods of preparing and using the antibodies are also disclosed.
申请公布号 WO2012143523(A1) 申请公布日期 2012.10.26
申请号 WO2012EP57303 申请日期 2012.04.20
申请人 GENMAB A/S;DE GOEIJ, BART;VAN BERKEL, PATRICK;STRUMANE, KRISTIN;LABRIJN, ARAN FRANK;NEIJSSEN, JOOST J.;MEESTERS, JOYCE I.;PARREN, PAUL;SCHUURMAN, JANINE 发明人 DE GOEIJ, BART;VAN BERKEL, PATRICK;STRUMANE, KRISTIN;LABRIJN, ARAN FRANK;NEIJSSEN, JOOST J.;MEESTERS, JOYCE I.;PARREN, PAUL;SCHUURMAN, JANINE
分类号 A61K39/395;A61P35/00;C07K16/10;C07K16/28;C07K16/32;C07K16/46 主分类号 A61K39/395
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